Description

Crotonoyl Coenzyme A Trilithium Salt is a high-purity, chemically defined biochemical reagent essential for metabolic research and enzymatic studies. This compound serves as a critical substrate or intermediate in the investigation of fatty acid metabolism, particularly in the study of β-oxidation pathways and acyl-CoA dehydrogenases. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic kit manufacturers requiring precise and reliable biochemical tools for their analytical and developmental work.

Application

• Biochemical Research: Used as a defined substrate in enzymatic assays to study the activity and kinetics of acyl-CoA dehydrogenases and other enzymes involved in fatty acid catabolism.
• Metabolic Pathway Analysis: A key intermediate for in vitro studies of the β-oxidation cycle, enabling researchers to map and understand energy production from fats.
• Pharmaceutical Development: Employed in drug discovery platforms targeting metabolic disorders, where it helps screen for modulators of specific metabolic enzymes.
• Diagnostic Reagent Manufacturing: Serves as a component in the formulation of clinical diagnostic kits designed to detect inborn errors of metabolism.
• Academic Research: Utilized in university and institutional labs for fundamental research into cellular bioenergetics and mitochondrial function.
• Enzyme Characterization: Acts as a standard or reference compound for the purification, identification, and functional characterization of novel enzymes.

Basic Information

Product Name	Crotonoyl Coenzyme A Trilithium Salt
CAS No.	102680-35-3
Molecular Formula	C₂₅H₄₀N₇O₁₇P₃S • 3Li
Molecular Weight	Approx. 869.6 g/mol (Free acid)
Synonyms	Crotonoyl-CoA trilithium salt; (E)-But-2-enoyl-CoA trilithium salt; trans-2-Butenoyl-coenzyme A trilithium salt; Crotonyl-CoA Li₃; S-Crotonoylcoenzyme A trilithium; Coenzyme A, S-crotonoyl-, trilithium salt; 2-Butenoyl-CoA (trilithium salt); trans-Crotonoyl-CoA
EINECS	Contact for details

Quality Control

Our Crotonoyl Coenzyme A Trilithium Salt is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to ensure it meets the stringent requirements for research-grade biochemicals. A detailed Certificate of Analysis (COA) providing batch-specific data on purity, identity, and impurities is supplied with every order to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.