Description

Coenzyme A Glutathione Disulfide, Sodium Salt is a critical biochemical reagent that plays a pivotal role in cellular redox metabolism. This compound is essential for researchers and manufacturers requiring a high-purity, stable form of the oxidized glutathione disulfide (GSSG) conjugate with Coenzyme A. It is primarily utilized in biochemical research, pharmaceutical development, and diagnostic applications where precise control of thiol-disulfide balance is required.

Application

• Biochemical Research: Used as a substrate or standard in enzymatic assays studying glutathione metabolism, redox signaling, and Coenzyme A-dependent pathways.
• Pharmaceutical Development: Serves as a key intermediate or reference material in the development of therapeutics targeting oxidative stress, such as in metabolic and neurodegenerative diseases.
• Diagnostic Reagent Manufacturing: Incorporated into diagnostic kits for the quantitative measurement of glutathione, glutathione peroxidase, and other redox-related enzymes in clinical and research settings.
• Cell Culture & Media Supplementation: Applied in specialized cell culture media to modulate the intracellular redox environment for studying cell signaling and apoptosis.
• Enzyme Activity Studies: Acts as a specific substrate for enzymes like glutathione reductase, facilitating the study of enzyme kinetics and inhibitor screening.

Basic Information

Product Name	Coenzyme A Glutathione Disulfide, Sodium Salt
CAS No.	102679-71-0
Molecular Formula	C27H45N9O21P3S2 • xNa
Molecular Weight	Approx. 1100 g/mol (Free Acid)
Synonyms	CoA-Glutathione Disulfide; CoA-SSG; Coenzyme A Mixed Disulfide with Glutathione; Glutathionyl-CoA Disulfide; CoASSG; Glutathione-CoA Disulfide; Coenzyme A and Glutathione Disulfide
EINECS	Contact for details

Quality Control

Our Coenzyme A Glutathione Disulfide, Sodium Salt is produced under stringent quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.