Description

n-[(2-Chloroethyl)Nitrosocarbamoyl]-L-Leucine Methyl Ester is a specialized synthetic organic compound belonging to the class of nitrosourea derivatives. This high-purity intermediate is critical for advanced research and development in medicinal chemistry and pharmacology. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel nitrosourea-based compounds for oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for potential chemotherapeutic agents.
• Biochemical Probe Development: Serves as a precursor for creating specialized probes to study alkylation mechanisms and DNA interaction.
• Fine Chemical Synthesis: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals for research applications.
• Academic & Institutional Research: Employed in university and government laboratories for investigating new anticancer mechanisms and drug delivery systems.

Basic Information

Product Name	n-[(2-Chloroethyl)Nitrosocarbamoyl]-L-Leucine Methyl Ester
CAS No.	102586-03-8
Molecular Formula	C11H20ClN3O4
Molecular Weight	293.75 g/mol
Synonyms	L-Leucine, N-[(2-chloroethyl)nitrosocarbamoyl]-, methyl ester; Methyl N-[(2-chloroethyl)nitrosocarbamoyl]-L-leucinate; 1-(2-Chloroethyl)-3-[(methoxycarbonyl)-L-leucyl]-1-nitrosourea; Nitrosourea leucine methyl ester derivative; NSC 364049; L-Leucine methyl ester nitrosocarbamoyl chloroethyl derivative
EINECS	Contact for details

Quality Control

Our n-[(2-Chloroethyl)Nitrosocarbamoyl]-L-Leucine Methyl Ester is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its light-sensitive nature, the container must be kept in opaque packaging or amber glass. Keep under inert atmosphere if long-term storage is required.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.