Description

4-(Trifluoromethylthio)Phenylacetic Acid is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. This compound is valued for its ability to introduce the lipophilic and electron-withdrawing trifluoromethylthio (SCF₃) group into target molecules, a key modification in modern agrochemical and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the SCF₃ group improves bioavailability and environmental stability.
• Material Science Research: Serves as a precursor for specialty monomers and ligands used in catalysis and advanced polymer systems.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring fluorinated motifs.

Basic Information

Product Name	4-(Trifluoromethylthio)Phenylacetic Acid
CAS No.	102582-93-4
Molecular Formula	C₉H₇F₃O₂S
Molecular Weight	236.21 g/mol
Synonyms	2-[4-(Trifluoromethylsulfanyl)phenyl]acetic acid; 4-(Trifluoromethylthio)benzeneacetic acid; (4-((Trifluoromethyl)thio)phenyl)acetic acid; α-Carboxy-4-(trifluoromethylthio)toluene; p-(Trifluoromethylthio)phenylacetic acid; SCAS Registry Number 102582-93-4
EINECS	Contact for details

Quality Control

Every batch of 4-(Trifluoromethylthio)Phenylacetic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, appropriate chemical handling procedures should be followed.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.