Description

Ethyl 1-[(4-Methylphenyl)Carbamoyl]-4-Phenyl-Piperidine-4-Carboxylate is a high-purity, synthetically valuable piperidine derivative. This compound serves as a critical advanced pharmaceutical intermediate in the research and development of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting the central nervous system.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and novel synthetic pathways.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial chemical entities.

Basic Information

Product Name	Ethyl 1-[(4-Methylphenyl)Carbamoyl]-4-Phenyl-Piperidine-4-Carboxylate
CAS No.	102395-71-1
Molecular Formula	C22H26N2O3
Molecular Weight	366.46 g/mol
Synonyms	Ethyl 1-(p-Tolylcarbamoyl)-4-phenylpiperidine-4-carboxylate; 4-Phenyl-1-[(4-methylphenyl)carbamoyl]piperidine-4-carboxylic Acid Ethyl Ester; 1-[(4-Methylphenyl)carbamoyl]-4-phenyl-4-piperidinecarboxylic Acid Ethyl Ester; 4-Phenyl-N-(p-tolyl)-4-piperidinecarboxamide-4-carboxylic Acid Ethyl Ester; Ethyl 4-Phenyl-1-(4-tolylcarbamoyl)piperidine-4-carboxylate; 102395-71-1; UNII-9J8F8Y2H6M
EINECS	Contact for details

Quality Control

Our Ethyl 1-[(4-Methylphenyl)Carbamoyl]-4-Phenyl-Piperidine-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.