Description

(S)-1-(2-Amino-1-Oxo-3-Phenylpropyl)-Piperidine CAS NO 102292-89-7 is a chiral piperidine derivative, a high-purity building block of significant value in advanced organic synthesis. Its core value lies in its role as a key intermediate for constructing complex, biologically active molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers in pharmaceutical R&D and fine chemical production who require high-quality, stereochemically defined intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and enzyme inhibitors due to its amino acid-like structure.
• Asymmetric Synthesis: Serves as a precursor or catalyst ligand in stereoselective chemical reactions to create enantiomerically pure compounds.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic agents.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals and advanced materials requiring specific stereochemistry.

Basic Information

Product Name	(S)-1-(2-Amino-1-Oxo-3-Phenylpropyl)-Piperidine
CAS No.	102292-89-7
Molecular Formula	C14H20N2O
Molecular Weight	232.33 g/mol
Synonyms	(S)-1-(2-Amino-3-phenylpropanoyl)piperidine; (S)-1-(2-Amino-1-oxo-3-phenylpropyl)piperidine; (S)-1-(2-Amino-3-phenyl-1-oxopropyl)piperidine; (S)-α-Amino-β-phenylpropionylpiperidine; (S)-2-Amino-3-phenyl-1-piperidin-1-ylpropan-1-one; L-2-Amino-3-phenyl-1-piperidin-1-ylpropan-1-one; (S)-3-Phenyl-2-(piperidine-1-carbonyl)alanine
EINECS	Contact for details

Quality Control

Our (S)-1-(2-Amino-1-Oxo-3-Phenylpropyl)-Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >98%), chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.