Description

Boc-Arg(Mts)-Oh is a protected derivative of the amino acid arginine, specifically designed for use in peptide synthesis. This compound is critical for researchers and manufacturers who require high-purity, selectively protected building blocks to construct complex peptides and bioconjugates. It is an essential intermediate for pharmaceutical R&D, particularly in the development of therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid building block for the sequential assembly of peptide chains, especially where the guanidine group of arginine requires specific protection.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies for producing custom peptides and peptide fragments in solution.
• Pharmaceutical Intermediate: Serves as a crucial raw material in the research and production of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation and Labeling: Facilitates the site-specific modification of peptides for creating fluorescent probes, affinity tags, or drug-linker constructs.
• Biochemical Research: Employed in academic and industrial laboratories for studying protein-protein interactions, enzyme substrates, and receptor ligands.
• Production of Protected Peptide Fragments: Used to synthesize shorter, protected sequences that are subsequently coupled to form larger target peptides.

Basic Information

Product Name	Boc-Arg(Mts)-Oh
CAS No.	102185-38-6
Molecular Formula	C19H30N4O6S
Molecular Weight	442.53 g/mol
Synonyms	Nα-Boc-NG-Mts-L-arginine; Boc-L-arginine(Mts)-OH; Nα-(tert-Butoxycarbonyl)-Nω-(2,3,5,6-tetramethylbenzenesulfonyl)-L-arginine; tert-Butyl N-[(2S)-5-[(2,3,5,6-tetramethylphenyl)sulfonylamino]-1-(carboxymethylamino)-1-oxopentan-2-yl]carbamate; Boc-Arg(Mts)-OH; Boc-L-Arg(Mts)-OH; Boc-Arg(Mts); Mts-Arg(Boc)-OH
EINECS	Contact for details

Quality Control

Our Boc-Arg(Mts)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.