Description

1,1,1-Trifluoro-4-Methoxy-3-Penten-2-One is a high-value fluorinated building block and versatile chemical intermediate. Its unique structure, featuring a trifluoromethyl ketone moiety and an enol ether, makes it a critical reagent for introducing fluorine atoms into complex molecules, thereby modifying their physical, chemical, and biological properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel compounds with enhanced metabolic stability, lipophilicity, and bioavailability.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display materials, enhancing their dielectric anisotropy and stability.
• Polymer & Coatings Modifier: Incorporated to create specialty fluoropolymers with improved solvent resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: A valuable building block for [3+2] cycloadditions and other reactions to construct complex heterocycles and fluorinated scaffolds in medicinal chemistry.
• Advanced Material Research: Employed in R&D for developing novel fluorinated dyes, sensors, and functional materials.

Basic Information

Product Name	1,1,1-Trifluoro-4-Methoxy-3-Penten-2-One
CAS No.	102145-82-4
Molecular Formula	C6H7F3O2
Molecular Weight	168.11 g/mol
Synonyms	4-Methoxy-1,1,1-trifluoro-3-penten-2-one; 1,1,1-Trifluoro-4-methoxypent-3-en-2-one; Trifluoroacetylacetone methyl ether; 4-Methoxy-1,1,1-trifluoropent-3-en-2-one; TFMPO; 3-Penten-2-one, 1,1,1-trifluoro-4-methoxy-
EINECS	Contact for details

Quality Control

Our 1,1,1-Trifluoro-4-Methoxy-3-Penten-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is sensitive to strong alkali and should be stored separately from incompatible materials such as bases and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.380 - 1.390
Density (20°C)	1.25 - 1.35 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.