Description

Bis(2-Chloroethyl)-D8-Amine Hcl is a deuterium-labeled analog of a key nitrogen mustard alkylating agent, specifically designed for research and analytical applications. This stable isotope-labeled compound is essential for use as an internal standard in mass spectrometry, enabling precise quantification and metabolic studies. It is primarily utilized by pharmaceutical researchers, forensic toxicologists, and analytical laboratories engaged in pharmacokinetics, drug metabolism, and environmental analysis.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis in bioanalytical studies.
• Metabolic pathway tracing and pharmacokinetic research in pharmaceutical development.
• Forensic analysis and toxicology screening for nitrogen mustard derivatives.
• Environmental monitoring and trace analysis of alkylating agent contaminants.
• Use in stable isotope dilution assays for enhanced accuracy and reproducibility.
• Research into the mechanisms and degradation products of chemical warfare agents.

Basic Information

Product Name	Bis(2-Chloroethyl)-D8-Amine Hcl
CAS No.	102092-04-6
Molecular Formula	C4D8H2Cl2N•HCl
Molecular Weight	Contact for details
Synonyms	Deuterated HN2 Hydrochloride; Nitrogen Mustard-d8 HCl; 2,2'-Dichloro-N,N-di(2-chloroethyl-d4)ethylamine Hydrochloride; Bis(2-chloroethyl-d4)amine Hydrochloride; Mechlorethamine-d8 HCl; Mustine-d8 Hydrochloride; Chlormethine-d8 HCl; DL-2,2'-Dichlorodiethyl-d8-amine Hydrochloride
EINECS	Contact for details

Quality Control

Our Bis(2-Chloroethyl)-D8-Amine Hcl is produced under strict quality management protocols to ensure high isotopic purity and chemical integrity. Each batch is characterized by advanced spectroscopic and chromatographic methods, including NMR and HPLC-MS. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D-atom %), chemical purity, and identity confirmation is provided with every shipment to support your research compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-atom %)	≥ 98.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.