Description

Pyridine, 3-(1H-Diazirin-1-Yl)- (9Ci) is a specialized heterocyclic compound featuring a pyridine ring substituted with a diazirine functional group. This unique structure makes it a valuable photoaffinity labeling reagent and a versatile chemical building block in advanced organic synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and life sciences sectors for developing novel bioactive molecules and probes.

Application

• Photoaffinity Labeling (PAL): A critical reagent for mapping biomolecular interaction sites and identifying drug targets due to its photoactivatable diazirine group.
• Chemical Biology & Proteomics: Used in the synthesis of probes for studying protein structure, function, and protein-ligand interactions.
• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Agrochemical Research: Employed in the design and synthesis of novel herbicides, pesticides, and plant growth regulators.
• Material Science: Potential use as a cross-linking agent or functional monomer in the development of advanced polymeric materials.
• Academic & Industrial R&D: A fundamental tool in organic chemistry laboratories for method development and complex molecule synthesis.

Basic Information

Item	Detail
Product Name	Pyridine, 3-(1H-Diazirin-1-Yl)- (9Ci)
CAS No.	102091-37-2
Molecular Formula	C6H5N3
Molecular Weight	119.12 g/mol
Synonyms	3-(Diazirin-1-yl)pyridine; 3-(1H-Diazirin-1-yl)pyridine; 3-Pyridinyldiaziridine; 3-Diazirinylpyridine; Diazirine, 1-(3-pyridinyl)-; Photoaffinity Labeling Reagent; PAL Reagent; 3-Pyridyl Diazirine
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity. Our production of Pyridine, 3-(1H-Diazirin-1-Yl)- adheres to in-house specifications developed for research-grade and process development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. For custom synthesis or specific grade requirements, our technical team is available to discuss tailored QC protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Research Grade)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.