Description

1,1-Dimethylethyl [2-Hydroxy-2-(1-Naphthalenyl)Ethyl]Carbamate is a specialized carbamate derivative featuring a naphthalene moiety, serving as a valuable protected intermediate in advanced organic synthesis. Its core value lies in enabling the controlled introduction of the 2-hydroxy-2-(1-naphthalenyl)ethylamine pharmacophore, a structural motif of interest in medicinal chemistry. This compound is primarily needed by research institutions and pharmaceutical development companies engaged in the synthesis of novel bioactive molecules, particularly for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or acting as enzyme inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the biological activity of naphthalene-containing compounds.
• Peptidomimetic Synthesis: Serves as a protected amine precursor for constructing non-peptide scaffolds that mimic peptide structure and function.
• Chiral Auxiliary/Resolving Agent Development: The chiral center and bulky groups make it a candidate for use in asymmetric synthesis or the resolution of enantiomers.
• Organic Light-Emitting Diode (OLED) Material Research: The conjugated naphthalene system allows for investigation into its photophysical properties for potential use in electronic materials.
• Agrochemical Intermediate: Potential use in the synthesis of novel herbicides or fungicides where the carbamate and naphthalene groups confer specific biological activity.

Basic Information

Product Name	1,1-Dimethylethyl [2-Hydroxy-2-(1-Naphthalenyl)Ethyl]Carbamate
CAS No.	102090-24-4
Molecular Formula	C₁₇H₂₁NO₃
Molecular Weight	287.36 g/mol
Synonyms	tert-Butyl [2-hydroxy-2-(naphthalen-1-yl)ethyl]carbamate; N-Boc-1-(1-naphthyl)ethanolamine; N-(tert-Butoxycarbonyl)-2-hydroxy-2-(1-naphthyl)ethylamine; 2-[(tert-Butoxycarbonyl)amino]-2-(1-naphthyl)ethanol; 1,1-Dimethylethyl N-[2-hydroxy-2-(1-naphthalenyl)ethyl]carbamate; Boc-1-Naphthylethanolamine; BOC-1-NEA; (RS)-tert-Butyl (2-hydroxy-2-(naphthalen-1-yl)ethyl)carbamate
EINECS	Contact for details

Quality Control

Our 1,1-Dimethylethyl [2-Hydroxy-2-(1-Naphthalenyl)Ethyl]Carbamate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.