Description

Tyr-D-Ala-p-Chloro-Phe-Pro-Nh2 CAS NO 102029-97-0 is a synthetic peptide derivative, specifically a modified pentapeptide, of significant interest in biochemical and pharmacological research. Its core value lies in its role as a potent and selective ligand for studying opioid receptor subtypes, providing critical insights into receptor binding and signal transduction mechanisms. This compound is essential for researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors focused on neurobiology, pain management, and peptide-based drug discovery.

Application

• Pharmacological Research: As a key tool compound for investigating the structure-activity relationships (SAR) of opioid peptides and receptors.
• Neuroscience Studies: Used in in vitro and ex vivo assays to probe the function and distribution of specific opioid receptor subtypes in the central nervous system.
• Drug Discovery & Development: Serves as a reference standard or a lead compound in the design and screening of novel analgesic and neuroprotective agents.
• Biochemical Assays: Employed in competitive binding studies and functional assays (e.g., GTPγS binding) to characterize receptor affinity and efficacy.
• Academic Research: A vital reagent for universities and research institutes conducting fundamental studies on peptide hormones, G-protein coupled receptors (GPCRs), and signal transduction pathways.
• Reference Standard: Used for quality control, method development, and validation in analytical laboratories working with synthetic peptides.

Basic Information

Item	Details
Product Name	Tyr-D-Ala-p-Chloro-Phe-Pro-Nh2
CAS No.	102029-97-0
Molecular Formula	C29H38ClN5O6
Molecular Weight	588.09 g/mol
Synonyms	Tyr-D-Ala-Phe(4-Cl)-Pro-NH2; [D-Ala2, p-Cl-Phe4]-Enkephalinamide; H-Tyr-D-Ala-Phe(4-Cl)-Pro-NH2; D-Ala2, p-Chloro-Phe4-Enkephalinamide; p-Chloro-Phe4-Enkephalin (D-Ala2, Pro5-NH2); Opioid peptide analog; 102029-97-0; CAS 102029-97-0
EINECS	Contact for details

Quality Control

Our Tyr-D-Ala-p-Chloro-Phe-Pro-Nh2 is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research-grade peptides, ensuring reliable performance in your experimental systems.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, the product should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.