Description

N6-([6-Aminohexyl]-Carbamoylmethyl)-Nicotinamide Adenine Dinucleotide Lithium Salt is a chemically modified coenzyme derivative designed for advanced biochemical research and diagnostic applications. This specialized NAD+ analog is engineered to facilitate covalent coupling to surfaces or carrier molecules, enabling the development of sensitive and stable enzymatic assays and biosensors. It is an essential reagent for researchers and manufacturers in the fields of life science research, in-vitro diagnostics (IVD), and pharmaceutical development, where precise enzyme activity measurement and detection are critical.

Application

• Enzyme-Linked Assay Development: Used as a substrate or cofactor in the development of colorimetric, fluorometric, and chemiluminescent assays for clinical diagnostics and high-throughput screening.
• Biosensor Fabrication: Serves as a key component for immobilizing dehydrogenase enzymes onto electrodes or chips to create biosensors for metabolite detection (e.g., glucose, lactate, ethanol).
• Protein Labeling & Conjugation: The reactive aminohexyl arm allows for covalent attachment to proteins, antibodies, or solid supports for studying enzyme kinetics or creating affinity matrices.
• Metabolic Pathway Research: A vital tool for investigating the role of NAD+-dependent enzymes in cellular metabolism, signaling, and aging-related studies.
• Diagnostic Kit Manufacturing: Incorporated as a core reagent in commercial diagnostic kits for liver function, cardiac markers, and other enzymatic tests requiring high stability and performance.
• Biocatalysis & Biotransformation: Employed in enzymatic synthesis processes where NAD+ regeneration is required for cost-effective production of chiral intermediates and fine chemicals.

Basic Information

Product Name	N6-([6-Aminohexyl]-Carbamoylmethyl)-Nicotinamide Adenine Dinucleotide Lithium Salt
CAS No.	102029-94-7
Molecular Formula	C28H42LiN7O14P2 (commonly cited for the lithium salt form)
Molecular Weight	Approx. 785.6 g/mol (Lithium Salt)
Synonyms	6-(6-Aminohexylcarbamoylmethyl)-NAD Lithium Salt; Aminohexyl-Carbamoylmethyl-NAD+; N6-Carboxymethyl-NAD+ 6-Aminohexylamide Lithium Salt; AHC-NAD+; NAD+-AHC; Modified NAD+; Coenzyme I derivative; β-NAD+ N6-[N-(6-Aminohexyl)carbamoylmethyl] Lithium Salt
EINECS	Contact for details

Quality Control

Our N6-([6-Aminohexyl]-Carbamoylmethyl)-Nicotinamide Adenine Dinucleotide Lithium Salt is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and functional performance. Certificates of Analysis (COA) are provided, detailing specifications for assay (HPLC), identity (UV/IR), moisture content, and related impurities. We support compliance with relevant guidelines for research and in-vitro diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (UV)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Functional Activity (Enzymatic Assay)	≥ 90% of theoretical activity
Solubility	Soluble in water or buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.