Description

Dl-Alanine-1-13C CAS NO 102029-81-2 is a stable isotope-labeled analog of the amino acid alanine, where the carbon at the 1-position is enriched with the 13C isotope. This compound is essential as an internal standard and tracer in advanced analytical and metabolic research, providing critical data for quantification and pathway analysis. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic manufacturers engaged in mass spectrometry, nuclear magnetic resonance (NMR) spectroscopy, and metabolic flux studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used for the precise quantification of alanine in complex biological matrices via LC-MS/MS and GC-MS methods.
• Metabolic Tracer in Biomedical Research: Enables the study of amino acid metabolism, protein synthesis rates, and gluconeogenesis pathways in cell cultures and animal models.
• NMR Spectroscopy Studies: Serves as a probe for structural and dynamic studies of proteins and enzymes due to the distinct 13C NMR signal.
• Pharmaceutical Development & Drug Metabolism: Employed in ADME (Absorption, Distribution, Metabolism, Excretion) studies to track the metabolic fate of new drug candidates.
• Clinical Diagnostics: Acts as a calibrant or reference material in developing diagnostic assays for metabolic disorders.
• Nutritional & Sports Science Research: Used to investigate muscle protein metabolism and the metabolic response to exercise and dietary interventions.

Basic Information

Product Name	Dl-Alanine-1-13C
CAS No.	102029-81-2
Molecular Formula	C313CH7NO2
Molecular Weight	90.09 g/mol (for 13C1 isotopologue)
Synonyms	(±)-2-Aminopropanoic-1-13C acid; DL-α-Alanine-1-13C; Alanine-1-13C (racemic); Racemic Alanine-1-13C; 1-13C-DL-Alanine; (RS)-2-Aminopropionic-1-13C acid; 2-Aminopropanoic-1-13C acid; DL-Alanine (1-13C)
EINECS	Contact for details

Quality Control

Our Dl-Alanine-1-13C is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity, critical for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (Atom % 13C), chemical purity, and specific analytical data from techniques such as NMR, MS, and HPLC. We adhere to cGMP guidelines for the production of research-grade labeled compounds, ensuring traceability, consistency, and reliability for your critical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % 13C)	≥ 99% at 1-position
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	N/A (racemic mixture)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.