Description

Acetoacetyl Coenzyme A Sodium Salt is a vital biochemical reagent, serving as a key substrate and intermediate in enzymatic studies and metabolic pathway research. Its primary value lies in enabling precise investigation into lipid biosynthesis, ketone body metabolism, and the mevalonate pathway. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require reliable, well-characterized cofactors for assay development and biochemical production.

Application

• Enzymatic Assay Substrate: Critical for in vitro studies of enzymes like HMG-CoA synthase, thiolase, and other acyl-CoA utilizing enzymes.
• Metabolic Pathway Research: Used to investigate and model the biosynthesis of cholesterol and isoprenoids via the mevalonate pathway.
• Pharmaceutical R&D: Serves as a key intermediate in screening and developing inhibitors for metabolic disorders and cholesterol-lowering drugs.
• Biochemical Production: Acts as a precursor in enzymatic synthesis for the production of specialized biochemicals and labeled compounds.
• Diagnostic Kit Manufacturing: Incorporated into diagnostic reagents and kits for measuring specific enzyme activities related to metabolic health.
• Academic Research: A fundamental tool in university and institutional labs for teaching and advanced research in biochemistry and molecular biology.

Basic Information

Product Name	Acetoacetyl Coenzyme A Sodium Salt
CAS No.	102029-52-7
Molecular Formula	C25H40N7O18P3S • xNa
Molecular Weight	Approx. 921.6 (Free acid)
Synonyms	Acetoacetyl-CoA Sodium Salt; S-Acetoacetylcoenzyme A Sodium Salt; 3-Oxobutanoyl-CoA; Acetoacetyl CoA; AcAc-CoA; Coenzyme A, S-acetoacetyl-, sodium salt; (S)-4'-Phosphopantothenoyl-3'-dephospho-CoA S-(3-oxobutanoate) sodium salt
EINECS	Contact for details

Quality Control

Our Acetoacetyl Coenzyme A Sodium Salt is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and production. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term stability, it is recommended to store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Enzymatic)	≥ 90% (of theoretical)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.