Description

Hemoglobin F-Cobb is a specialized biochemical reagent, a purified form of fetal hemoglobin. This high-purity compound is critical for research and diagnostic applications requiring a specific and well-characterized protein standard. It serves as an essential reference material for scientists and quality control professionals in the life sciences. Key industries utilizing this product include biotechnology, clinical diagnostics, and pharmaceutical research.

Application

• Reference Standard for Diagnostic Assays: Used to calibrate and validate laboratory tests for hemoglobinopathies, such as sickle cell disease and thalassemia.
• Biochemical Research: Serves as a key reagent in studies investigating oxygen transport, hemoglobin switching, and fetal development.
• Quality Control in Pharmaceutical Manufacturing: Employed as a process control standard in the production of blood-based therapeutics and related biologics.
• Clinical Laboratory Internal Controls: Provides a known-value control material for ensuring the accuracy of high-performance liquid chromatography (HPLC) and electrophoresis systems.
• Development of In-Vitro Diagnostics (IVD): Essential for the research, development, and lot-to-lot consistency testing of diagnostic kits and instruments.
• Hematology Studies: Used to study the structural and functional properties of fetal hemoglobin compared to adult hemoglobin.

Basic Information

Product Name	Hemoglobin F-Cobb
CAS No.	101800-50-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fetal Hemoglobin Cobb; Hb F-Cobb; Hemoglobin F (Cobb variant); Fetal Hb Standard Cobb; Cobb Variant Hemoglobin F; Human Fetal Hemoglobin Cobb; HbF Cobb; Diagnostic Grade Hemoglobin F
EINECS	Contact for details

Quality Control

Our Hemoglobin F-Cobb is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and physical characteristics is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at controlled room temperature or as specified on the label or Certificate of Analysis. Keep the container sealed in a dry environment to maintain integrity.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (HPLC/Electrophoresis)	Conforms to standard
Purity (HPLC)	≥ 95%
Assay (Spectrophotometric)	90% - 110% of labeled concentration
Solubility	Clear solution in specified buffer
Endotoxin	< 1.0 EU/mg (where applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.