Description

1,24,26-Trihydroxy-Delta 22-Vitamin D3 is a high-purity, biologically active vitamin D3 metabolite. This compound is a critical intermediate and reference standard in advanced pharmaceutical research and development, particularly for studying calcium metabolism and cell differentiation. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries focused on metabolic bone disorders and endocrine therapies.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant in analytical methods (HPLC, LC-MS) for quality control and research.
• Active Pharmaceutical Ingredient (API) Intermediate: A key synthetic precursor in the manufacture of advanced vitamin D analogs and metabolites.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate vitamin D receptor (VDR) signaling pathways and gene regulation.
• Metabolic Studies: Critical for research into calcium and phosphate homeostasis, bone mineralization, and related endocrine functions.
• Cell Culture & Differentiation: Used in laboratory settings to study its effects on cell proliferation and differentiation in various cell lines.
• Nutraceutical R&D: Serves as a benchmark compound in the development of advanced dietary supplements targeting bone health.

Basic Information

Product Name	1,24,26-Trihydroxy-Delta 22-Vitamin D3
CAS No.	101558-90-1
Molecular Formula	C₂₇H₄₂O₄
Molecular Weight	430.62 g/mol
Synonyms	1,24,26-Trihydroxy-22-dehydrovitamin D3; 1α,24R,26-Trihydroxy-22E-ergosta-5,7,22-trien-3β-ol; δ-22-1,24,26-TriOH Vitamin D3; (1α,3β,5Z,7E,22E)-9,10-Secocholesta-5,7,10(19),22-tetraene-1,3,24,26-tetrol; 22-Dehydro-1,24,26-trihydroxyvitamin D3; 1,24,26-Trihydroxyvitamin D3 22-ene
EINECS	Contact for details

Quality Control

Our 1,24,26-Trihydroxy-Delta 22-Vitamin D3 is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for research and pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) or as specified on the label or COA. This product is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.