Description

1-Propanone, 2,2-Dichloro-1-(4-Fluorophenyl)- (9Ci) is a specialized halogenated aromatic ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both dichloro and fluoro substituents, makes it a valuable precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Serves as a crucial building block for creating advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Used in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its ability to modify molecular polarity and intermolecular interactions.
• Chemical Biology Probe Development: Employed as a scaffold for creating molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-Propanone, 2,2-Dichloro-1-(4-Fluorophenyl)- (9Ci)
CAS No.	101530-91-0
Molecular Formula	C9H7Cl2FO
Molecular Weight	221.06 g/mol
Synonyms	2,2-Dichloro-1-(4-fluorophenyl)propan-1-one; 4-Fluoro-α,α-dichloropropiophenone; 1-(4-Fluorophenyl)-2,2-dichloropropan-1-one; 2,2-Dichloro-1-(p-fluorophenyl)-1-propanone; p-Fluoro-α,α-dichloropropiophenone; α,α-Dichloro-4-fluoropropiophenone; 4-Fluorophenyldichloroethyl ketone; 101530-91-0
EINECS	Contact for details

Quality Control

We supply 1-Propanone, 2,2-Dichloro-1-(4-Fluorophenyl)- (9Ci) in high-purity grades suitable for research and development. Every batch undergoes rigorous analytical characterization using techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality management system supports cGMP and ISO standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.