Description

Benzoyl Fluoride, 2,4,5-Trifluoro- (9Ci) is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the benzoyl fluoride core, which allows for precise modification of molecular properties in target compounds. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) where fluorine substitution is used to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl and fluorine groups can enhance activity and environmental persistence profiles.
• Liquid Crystal & Electronic Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals and organic semiconductors, contributing to improved performance in display technologies and electronic devices.
• Polymer Chemistry: Employed as a monomer or modifier in the synthesis of specialty polymers, including high-performance resins and coatings with enhanced chemical resistance and thermal stability.
• Organic Synthesis Building Block: Utilized in various name reactions and coupling chemistries to introduce the 2,4,5-trifluorobenzoyl moiety into more complex molecular architectures.
• Research & Development: Critical for medicinal chemistry programs and material science research exploring structure-activity relationships (SAR) influenced by specific fluorine patterns.

Basic Information

Product Name	Benzoyl Fluoride, 2,4,5-Trifluoro- (9Ci)
CAS No.	101513-67-1
Molecular Formula	C7H2F4O
Molecular Weight	178.09 g/mol
Synonyms	2,4,5-Trifluorobenzoyl Fluoride; 2,4,5-Trifluorobenzoic Acid Fluoride; Benzoyl Fluoride, 2,4,5-trifluoro-; 2,4,5-Trifluorobenzoyl Fluoride (9CI); 2,4,5-Trifluoro-1-(fluorocarbonyl)benzene; 2,4,5-Trifluorobenzoic Fluoride; 2,4,5-Trifluorobenzene-1-carbonyl Fluoride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards and customer-specific requirements. Each batch is analyzed using advanced techniques including GC, HPLC, NMR, and IR spectroscopy to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) documenting all relevant specifications are available upon request, providing full traceability and supporting cGMP and ISO quality management principles where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.