Description

n-(Tosyl-L-Alanyl)-3-Hydroxyindole is a specialized synthetic organic compound featuring a tosyl-protected L-alanine moiety linked to a 3-hydroxyindole scaffold. This molecular architecture makes it a valuable building block and key intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of peptidomimetics and other complex drug candidates.
• Protease Inhibitor Research: Used in the development and study of enzyme inhibitors due to its peptide-like structure.
• Medicinal Chemistry: Acts as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Bioconjugation: Employed in the design of labeled compounds or probes for biochemical assays.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for exploratory synthetic chemistry projects.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for clients.

Basic Information

Product Name	n-(Tosyl-L-Alanyl)-3-Hydroxyindole
CAS No.	101506-88-1
Molecular Formula	C19H20N2O4S
Molecular Weight	372.44 g/mol
Synonyms	N-[(4-Methylphenyl)sulfonyl]-L-alanyl-3-hydroxy-1H-indole; 3-Hydroxy-1H-indole-1-[(4-methylphenyl)sulfonyl]-L-alanine; L-Alanine, N-[(4-methylphenyl)sulfonyl]-, 3-hydroxy-1H-indol-1-yl ester; Tosyl-L-alanyl-3-hydroxyindole; N-Tosyl-L-alanyl-3-hydroxyindole; 1H-Indol-3-ol, 1-[[(2S)-2-[[(4-methylphenyl)sulfonyl]amino]-1-oxopropyl]]-
EINECS	Contact for details

Quality Control

Our n-(Tosyl-L-Alanyl)-3-Hydroxyindole is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. For research and development purposes, we can supply material meeting standard laboratory-grade specifications, with options for higher purity grades available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.