Description

5-Chloro-2-Methyl-4-Nitrobenzonitrile is a versatile nitrile-substituted aromatic compound that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring chloro, methyl, and nitro functional groups, makes it a valuable precursor for creating complex molecules with tailored properties. This intermediate is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzonitrile core.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides, where its functional groups allow for structural diversification.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex azo dyes and high-performance pigments.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Suzuki, Heck) due to the reactivity of the nitrile and halogen groups.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways and creating compound libraries for screening.

Basic Information

Product Name	5-Chloro-2-Methyl-4-Nitrobenzonitrile
CAS No.	101495-54-9
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	4-Nitro-5-chloro-2-methylbenzonitrile; 2-Methyl-4-nitro-5-chlorobenzonitrile; 5-Chloro-2-methyl-4-nitrobenzonitrile; Benzonitrile, 5-chloro-2-methyl-4-nitro-; 5-Chloro-2-methyl-4-nitro-benzonitrile
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Methyl-4-Nitrobenzonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification results. Our quality commitment ensures the material meets the high standards required for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.