Description

Oxymorphone 4-Nitrophenylhydrazone CAS NO 101365-17-7 is a specialized chemical derivative of the potent opioid analgesic oxymorphone, formed by reaction with 4-nitrophenylhydrazine. This compound is of significant value as a key reference standard and analytical intermediate in pharmaceutical research and forensic toxicology. It is primarily required by research laboratories, pharmaceutical development companies, and forensic science institutions for method development, calibration, and the qualitative/quantitative analysis of opioid substances and their metabolites.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments (HPLC, GC-MS, LC-MS) in drug development and quality control.
• Forensic Toxicology: Serves as a critical comparative standard for the identification and confirmation of oxymorphone and related opioids in biological samples.
• Metabolite Studies: Employed in research to study the metabolism, pharmacokinetics, and detection windows of opioid analgesics.
• Method Development & Validation: Essential for developing and validating sensitive and specific analytical methods in compliance with regulatory guidelines (e.g., FDA, EMA).
• Chemical Synthesis Intermediate: Acts as a precursor or derivative in specialized organic synthesis for creating novel compounds for pharmacological evaluation.
• Academic Research: Utilized in university and institutional research focused on opioid receptor interactions, analgesic pathways, and substance abuse science.

Basic Information

Product Name	Oxymorphone 4-Nitrophenylhydrazone
CAS No.	101365-17-7
Molecular Formula	C24H26N4O5
Molecular Weight	450.49 g/mol
Synonyms	14-Hydroxydihydromorphinone 4-nitrophenylhydrazone; 4,5α-Epoxy-3,14-dihydroxy-17-methylmorphinan-6-one 4-nitrophenylhydrazone; Oxymorphone p-nitrophenylhydrazone; Oxymorphone PNPH derivative; Numorphan 4-nitrophenylhydrazone; Opana 4-NPH derivative
EINECS	Contact for details

Quality Control

Our Oxymorphone 4-Nitrophenylhydrazone is produced and handled under strict quality protocols suitable for analytical and research purposes. Each batch undergoes rigorous identity confirmation and purity analysis using techniques including HPLC, NMR, and mass spectrometry. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data upon request, ensuring traceability and compliance with your research or method validation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.