Description

2-Chloro-4-Fluoroiodobenzene is a high-purity halogenated benzene derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique combination of chlorine, fluorine, and iodine substituents makes it a valuable precursor for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for cross-coupling reactions and functional group transformations.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions for synthesizing novel drug candidates and APIs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Liquid Crystal & OLED Materials: Serves as a building block for creating halogenated aromatic cores in electronic and display materials.
• Organic Ligand Preparation: Utilized in the synthesis of specialized ligands for catalysis and coordination chemistry.
• Chemical Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic pathways and creating functionalized aromatics.
• Fluorine Chemistry: The presence of both fluorine and iodine makes it a unique substrate for further selective fluorination and functionalization studies.

Basic Information

Product Name	2-Chloro-4-Fluoroiodobenzene
CAS No.	101335-11-9
Molecular Formula	C6H3ClFI
Molecular Weight	256.44 g/mol
Synonyms	1-Chloro-2-fluoro-4-iodobenzene; 2-Chloro-1-fluoro-4-iodobenzene; 4-Fluoro-2-chloroiodobenzene; Benzene, 2-chloro-4-fluoro-1-iodo-; 2-Chloro-4-fluoro-1-iodobenzene; 1-Iodo-2-chloro-4-fluorobenzene; (2-Chloro-4-fluorophenyl)iodide
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoroiodobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for use in pharmaceutical and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.