Description

3-Bromopropionic Acid n-Hydroxysuccinimide is a high-purity, reactive ester derivative used as a critical bifunctional linker in organic synthesis and bioconjugation. This compound matters for its ability to efficiently introduce a bromoalkyl chain, serving as a versatile intermediate for creating custom molecules with specific functionalities. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications ranging from drug development to polymer modification.

Application

• Bioconjugation Reagent: Used to attach small molecules, peptides, or labels to biomolecules like proteins and antibodies via amine groups.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs.
• Crosslinking Agent: Employed in polymer chemistry and material science to create crosslinked networks or functionalized surfaces.
• Peptide Synthesis: Acts as a coupling reagent or a side-chain modifier in solid-phase peptide synthesis (SPPS).
• Affinity Chromatography Ligand Preparation: Used to immobilize specific ligands onto chromatographic supports.
• Chemical Probe Development: Facilitates the creation of probes for studying biological processes and target identification.

Basic Information

Product Name	3-Bromopropionic Acid n-Hydroxysuccinimide
CAS No.	101314-84-5
Molecular Formula	C7H8BrNO4
Molecular Weight	250.05 g/mol
Synonyms	3-Bromopropionic Acid N-Hydroxysuccinimide Ester; 3-Bromopropionic Acid NHS Ester; N-(3-Bromopropionyloxy)succinimide; 2,5-Dioxopyrrolidin-1-yl 3-bromopropanoate; 3-Bromopropanoic Acid Succinimidyl Ester; Bromopropionyl NHS Ester; 3-Bromo-N-succinimidopropionate
EINECS	Contact for details

Quality Control

Our 3-Bromopropionic Acid n-Hydroxysuccinimide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.