Description

Glycine, N-(4-Aminobenzoyl)-, Methyl Ester, Monohydrochloride is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical building block for the controlled construction of complex peptides and other bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediates: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and complex peptide-based drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected glycine derivative to ensure regioselective coupling.
• Bioconjugation Chemistry: Acts as a linker or spacer molecule for attaching functional groups, dyes, or drugs to proteins, antibodies, or other biomolecules.
• Proteomics Research: Employed in the study of protein structure, function, and interactions within academic and industrial R&D settings.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for investigating biological pathways and enzyme activity.
• Agrochemical Research: Serves as an intermediate in the development of novel, targeted crop protection agents and plant growth regulators.

Basic Information

Product Name	Glycine, N-(4-Aminobenzoyl)-, Methyl Ester, Monohydrochloride
CAS No.	101248-38-8
Molecular Formula	C10H13N2O3•HCl
Molecular Weight	244.68 g/mol
Synonyms	4-Aminobenzoylglycine Methyl Ester Hydrochloride; Methyl (4-Aminobenzamido)acetate Hydrochloride; Glycine, N-(p-aminobenzoyl)-, methyl ester, hydrochloride; Methyl 2-[(4-aminobenzoyl)amino]acetate hydrochloride; p-Aminohippuric Acid Methyl Ester Hydrochloride; N-(4-Aminobenzoyl)glycine Methyl Ester HCl; Hippurylglycine Methyl Ester Hydrochloride
EINECS	Contact for details

Quality Control

Our Glycine, N-(4-Aminobenzoyl)-, Methyl Ester, Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.