Description

α-Cgrp (19-37) (Human) is a defined peptide fragment of the human Calcitonin Gene-Related Peptide (CGRP). This high-purity reference standard is critical for research and development in neurobiology and pharmacology. It is primarily utilized by pharmaceutical R&D teams and academic researchers for biochemical studies, assay development, and as a key analytical standard. The product is supplied with comprehensive documentation to ensure traceability and reliability for sensitive applications.

Application

• Biochemical Research: Used as a reference standard in studies investigating the structure, function, and receptor interactions of CGRP and its fragments.
• Assay Development & Validation: Serves as a critical component in the development and calibration of immunoassays (ELISA, RIA) and bioassays targeting CGRP activity.
• Pharmaceutical R&D: Employed in drug discovery programs focused on migraine, cardiovascular disorders, and inflammation where CGRP pathways are a therapeutic target.
• Neuroscience Studies: Applied in experimental models to understand the role of specific CGRP domains in neuronal signaling and pain perception.
• Quality Control: Acts as a system suitability standard in analytical methods (e.g., HPLC, LC-MS) for related peptide-based pharmaceuticals or research materials.

Basic Information

Product Name	α-Cgrp (19-37) (Human)
CAS No.	101233-12-9
Molecular Formula	C92H147N29O26S2
Molecular Weight	2099.4 g/mol
Synonyms	Human α-CGRP (19-37); Calcitonin Gene-Related Peptide, α-(19-37)-peptide (human); α-CGRP19–37 (human); CGRP-I (19-37); h-α-CGRP(19-37); Tyr-Calcitonin Gene-Related Peptide (19-37) (human); [Tyr0]-α-CGRP (19-37) (human); α-Calcitonin Gene-Related Peptide Fragment 19-37 (Human)
EINECS	Contact for details

Quality Control

Every batch of α-Cgrp (19-37) (Human) is manufactured and tested under strict quality management systems. The product undergoes rigorous analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from multiple orthogonal methods including HPLC for purity and MS for identity confirmation. Our quality commitment aligns with the standards expected for premium research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This material is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.