Description

Benzonitrile, 4-[(1R)-1-Hydroxyethyl]- (9Ci) CAS NO 101219-69-6 is a chiral benzonitrile derivative featuring a hydroxyl group on the ethyl side chain, making it a versatile chiral building block and intermediate in advanced organic synthesis. This compound is valued for its role in constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and specialty chemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for applications requiring high-purity, enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides where specific stereochemistry impacts biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands used in asymmetric catalysis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring precise molecular architecture.
• Academic and R&D: A valuable compound for methodological development in organic chemistry and stereoselective synthesis research.
• Material Science: Potential intermediate for creating chiral monomers or additives for advanced polymeric materials.

Basic Information

Item	Details
Product Name	Benzonitrile, 4-[(1R)-1-Hydroxyethyl]- (9Ci)
CAS No.	101219-69-6
Molecular Formula	C9H9NO
Molecular Weight	147.17 g/mol
Synonyms	(R)-4-(1-Hydroxyethyl)benzonitrile; (1R)-1-(4-Cyanophenyl)ethanol; p-[(1R)-1-Hydroxyethyl]benzonitrile; (R)-1-(4-Cyanophenyl)ethanol; 4-[(R)-1-Hydroxyethyl]benzonitrile; (+)-1-(4-Cyanophenyl)ethanol; (R)-p-Hydroxyethylbenzonitrile; Benzonitrile, 4-[(R)-1-hydroxyethyl]-
EINECS	Contact for details

Quality Control

Our Benzonitrile, 4-[(1R)-1-Hydroxyethyl]- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity (enantiomeric excess) and chemical purity assays, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.