Description

2-(4-Bromophenyl)-2-Methylpropanenitrile is a versatile brominated aromatic nitrile compound, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a sterically hindered benzylic position and a reactive nitrile group, enabling the construction of complex molecular architectures. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors, facilitating the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the bromophenyl moiety for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized phosphine ligands or metal-organic frameworks (MOFs) in catalysis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, or polymers with specific electronic or optical properties.
• Chemical Biology Probes: Utilized as a scaffold for creating molecular probes and tags used in biochemical assay development and diagnostic research.
• Custom Synthesis and R&D: A valuable starting material for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Item	Details
Product Name	2-(4-Bromophenyl)-2-Methylpropanenitrile
CAS No.	101184-73-0
Molecular Formula	C10H10BrN
Molecular Weight	224.10 g/mol
Synonyms	2-(4-Bromophenyl)-2-methylpropionitrile; α,α-Dimethyl-4-bromobenzeneacetonitrile; p-Bromo-α,α-dimethylbenzyl cyanide; 4-Bromo-α,α-dimethylbenzeneacetonitrile; (4-Bromophenyl)(cyano)dimethylmethane; 2-Methyl-2-(4-bromophenyl)propanenitrile; 2-(p-Bromophenyl)-2-methylpropionitrile
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Bromophenyl)-2-Methylpropanenitrile is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, guaranteeing it meets the stringent requirements for research and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.