Description

Cholecystokinin C-Terminal Flanking Peptide is a synthetic peptide fragment corresponding to the C-terminal region of the cholecystokinin (CCK) prohormone. This compound is a critical research tool for studying the biosynthesis, processing, and physiological roles of CCK, a major gastrointestinal hormone and neurotransmitter. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and diagnostic developers in the fields of neuroendocrinology, gastroenterology, and metabolic disease research.

Application

• Biochemical Research: Used as a reference standard and antigen in studies of cholecystokinin biosynthesis, post-translational processing, and peptide hormone maturation.
• Antibody Production: Serves as an immunogen for generating specific polyclonal or monoclonal antibodies against CCK and its precursor fragments for immunoassay development.
• Diagnostic Development: Employed in the calibration and validation of ELISA, RIA, and other immunoassay kits designed to measure CCK or related peptides in biological samples.
• Neuroscience Studies: Applied in research investigating the role of CCK in brain function, including its interactions with dopamine systems and implications in anxiety and satiety.
• Gastrointestinal Physiology: A key reagent for exploring CCK's functions in pancreatic enzyme secretion, gallbladder contraction, and gut motility.
• Pharmaceutical Screening: Used in assay systems to identify and characterize potential modulators of the CCK receptor pathway.

Basic Information

Product Name	Cholecystokinin C-Terminal Flanking Peptide
CAS No.	101162-62-3
Molecular Formula	C₈₀H₁₂₈N₂₄O₂₄S₂
Molecular Weight	1882.1 g/mol
Synonyms	CCK-58 (1-8); Cholecystokinin-58 (1-8); CCK Flanking Peptide; CCK-58 Fragment (1-8); Prepro-CCK (1-8); CCK Prohormone Fragment; Cholecystokinin Precursor Fragment; Tyr-Ile-Gln-Gln-Ala-Arg-Lys-Ala (YIQQARKA)
EINECS	Contact for details

Quality Control

Our Cholecystokinin C-Terminal Flanking Peptide is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reproducible and reliable results for your critical studies.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.