Description

Histatin 1 is a naturally occurring antimicrobial peptide found in human saliva, playing a crucial role in the innate immune defense of the oral cavity. This compound is of significant interest for its potent antifungal and antibacterial properties, particularly against Candida albicans. As a high-purity biochemical, it is essential for researchers and developers in the pharmaceutical, biotechnology, and advanced oral care industries, where it serves as a key active ingredient or reference standard for studying host defense mechanisms and developing novel therapeutic agents.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of innate immunity, peptide biochemistry, and host-pathogen interactions.
• Antifungal Agent Development: Serves as a lead compound for developing novel therapeutic agents targeting oral candidiasis and other fungal infections.
• Oral Care Product Formulation: Incorporated into advanced mouthwashes, toothpastes, and gels for its natural antimicrobial and wound-healing properties.
• Dental Material Coating: Applied to dental implants and prosthetics to create bioactive surfaces that resist microbial colonization and biofilm formation.
• Pharmaceutical Intermediate: Utilized in the synthesis and development of peptide-based drugs and diagnostic tools.
• Cosmeceutical Applications: Explored for use in skincare formulations for its potential antimicrobial and regenerative effects.

Basic Information

Product Name	Histatin 1
CAS No.	101056-53-5
Molecular Formula	C185H301N63O55
Molecular Weight	4268.8 g/mol
Synonyms	Histatin-1; Salivary Histatin 1; Histatin 1 (human); Hst1; Antimicrobial Peptide Histatin 1; Human Salivary Peptide Histatin 1; P15570
EINECS	Contact for details

Quality Control

Our Histatin 1 is produced under stringent quality management systems to ensure the highest standards of purity and consistency. Each batch is subjected to comprehensive analytical testing, including High-Performance Liquid Chromatography (HPLC) for purity assessment and Mass Spectrometry (MS) for identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the material desiccated. Allow the vial to warm to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Biological Activity	Assayed (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.