Description

Gastrin I (1-14) (Human) is a synthetic tetradecapeptide fragment corresponding to the N-terminal sequence of the human gastrin I hormone. This high-purity peptide is critical for biochemical research and pharmaceutical development, serving as a precise reference standard and active pharmaceutical ingredient (API) intermediate. It is primarily utilized by research institutions, diagnostic manufacturers, and pharmaceutical companies focused on gastrointestinal physiology, hormone receptor studies, and therapeutic agent development.

Application

• Biomedical Research: Used as a reference standard in studies of gastrin's biological activity, receptor binding assays, and signal transduction pathways.
• Pharmaceutical Development: Serves as a key intermediate or starting material in the synthesis of longer gastrin analogs or related therapeutic peptides.
• Diagnostic Reagents: Employed in the development and calibration of immunoassays (ELISA, RIA) for measuring gastrin levels in clinical samples.
• Cell Culture & Physiology: Applied in *in vitro* studies to stimulate gastric acid secretion or examine effects on gastrointestinal cell lines.
• Quality Control: Acts as a system suitability standard in analytical laboratories for method validation and HPLC/UPLC performance qualification.
• Academic Studies: Utilized in university and institutional research exploring the structure-function relationship of gastrointestinal hormones.

Basic Information

Product Name	Gastrin I (1-14) (Human)
CAS No.	100940-57-6
Molecular Formula	C78H104N18O22S2
Molecular Weight	1742.0 g/mol
Synonyms	Human Gastrin I (1-14); Gastrin I Fragment 1-14; pGlu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp; Pyr-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp; L-Pyroglutamyl-glycyl-L-prolyl-L-tryptophyl-L-leucyl-L-glutamyl-L-glutamyl-L-glutamyl-L-glutamyl-L-glutamyl-L-alanyl-L-tyrosyl-glycyl-L-tryptophan; HG-14; Gastrin-14
EINECS	Contact for details

Quality Control

Our Gastrin I (1-14) (Human) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) are available for every lot, detailing purity, content, and residual solvent data. Our quality commitment ensures material suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to warm to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by AAA)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.