Description

2':3'-Cyclic Nadp Sodium Salt is a specialized biochemical coenzyme derivative, a cyclic analog of nicotinamide adenine dinucleotide phosphate (NADP+). This compound is of significant value in biochemical research and diagnostic applications, serving as a stable, non-hydrolyzable substrate or inhibitor for NADP+-dependent enzymes. It is primarily utilized by researchers and manufacturers in the fields of enzymology, metabolic pathway analysis, and in vitro diagnostic (IVD) kit development, where precise control over redox reactions is critical.

Application

• Enzymology Research: Used as a specific substrate or competitive inhibitor for studying the kinetics and mechanisms of NADP+-dependent dehydrogenases and reductases.
• Diagnostic Reagent Manufacturing: A key component in the formulation of reagents for clinical chemistry analyzers to measure specific enzyme activities (e.g., glucose-6-phosphate dehydrogenase).
• Metabolic Studies: Employed in cell-free systems to investigate the pentose phosphate pathway and other NADPH-dependent biosynthetic processes.
• Pharmaceutical Screening: Utilized in high-throughput screening assays to identify potential modulators of NADP+-utilizing enzymes as drug targets.
• Biochemical Standard: Serves as a certified reference material for the calibration and validation of analytical methods in quality control laboratories.

Basic Information

Product Name	2':3'-Cyclic Nadp Sodium Salt
CAS No.	100929-77-9
Molecular Formula	C21H25N7NaO17P3
Molecular Weight	787.36 g/mol
Synonyms	2',3'-cNADP Sodium Salt; Cyclic NADP Na Salt; 2':3'-Cyclic Nicotinamide-Adenine Dinucleotide Phosphate Sodium Salt; cNADP-Na; NADP+ 2':3'-cyclic phosphate sodium salt; 2',3'-Cyclic NADP+; Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium, inner salt, 2',3'-cyclic phosphate, sodium salt
EINECS	Contact for details

Quality Control

Our 2':3'-Cyclic Nadp Sodium Salt is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research and diagnostic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and specific impurities is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.