Description

Carbamic Acid, [(1R)-1-Cyanoethyl]-, 1,1-Dimethylethyl Ester (9Ci) is a specialized chiral intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the production of enantiomerically pure pharmaceuticals and agrochemicals, where stereochemical integrity is paramount. It is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in routes requiring the introduction of a cyanoethyl moiety with defined stereochemistry.
• Agrochemical Synthesis: Used in the research and production of advanced, stereoselective pesticides and herbicides.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for asymmetric transformations.
• Peptidomimetics & Bioactive Molecules: Employed in the construction of complex molecular architectures for drug discovery programs targeting various disease pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	Carbamic Acid, [(1R)-1-Cyanoethyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	100927-09-1
Molecular Formula	C10H18N2O2
Molecular Weight	198.26 g/mol
Synonyms	(R)-1-Cyanoethyl tert-butylcarbamate; tert-Butyl N-[(1R)-1-cyanoethyl]carbamate; (R)-tert-Butyl (1-cyanoethyl)carbamate; (R)-1-(tert-Butoxycarbonylamino)propionitrile; BOC-(R)-Ala(CN)-OtBu; (R)-2-((tert-Butoxycarbonyl)amino)butanenitrile (related isomer); N-Boc-(R)-2-aminobutyronitrile; (1R)-1-Cyanoethylcarbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(1R)-1-Cyanoethyl]-, 1,1-Dimethylethyl Ester (9Ci) is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your research or cGMP needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.