Description

α-Acetamido-n-Isobutyl-β-Phenylacrylamide is a specialized organic compound with the CAS number 100908-60-9. This molecule is a key chiral intermediate of significant value in the synthesis of complex pharmaceuticals and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients. Its unique structure makes it a versatile building block for creating compounds with specific biological activity.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where its structural motifs can contribute to targeted biological activity.
• Fine Chemical Synthesis: Serves as a versatile precursor in organic synthesis for creating complex molecules with specific stereochemistry in laboratory and pilot-scale production.
• Biochemical Research: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Custom Synthesis Projects: A valuable starting material for contract research and manufacturing organizations (CROs/CMOs) working on proprietary synthesis routes.

Basic Information

Product Name	α-Acetamido-n-Isobutyl-β-Phenylacrylamide
CAS No.	100908-60-9
Molecular Formula	C₁₇H₂₄N₂O₂
Molecular Weight	288.39 g/mol
Synonyms	(E)-N-(2-Methylpropyl)-2-(acetylamino)-3-phenyl-2-propenamide; 2-Acetamido-3-phenyl-N-isobutylacrylamide; (E)-2-Acetamido-3-phenylacrylic Acid Isobutylamide; α-Acetamido-β-phenyl-N-isobutylacrylamide; NSC 405124; (E)-N-Isobutyl-2-acetamido-3-phenylacrylamide; 2-(Acetylamino)-3-phenyl-2-propenoic Acid 2-Methylpropylamide
EINECS	Contact for details

Quality Control

Our α-Acetamido-n-Isobutyl-β-Phenylacrylamide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.