Description

Ethyl 2-Bromo-2-(2-Fluorophenyl)Acetate is a versatile fluorinated bromoacetate ester, a key synthetic intermediate in modern organic chemistry. Its molecular structure, featuring both bromine and fluorine substituents on an aromatic acetic acid backbone, makes it a valuable electrophile and building block for constructing complex molecules. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries. It enables the efficient introduction of functionalized phenylacetic acid derivatives into target molecules, facilitating the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated phenylacetic acid moiety.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials that incorporate halogenated aromatic units for specific electronic or physical properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags that study biological systems, leveraging the reactivity of the bromoacetate group.

Basic Information

Product Name	Ethyl 2-Bromo-2-(2-Fluorophenyl)Acetate
CAS No.	100638-28-6
Molecular Formula	C10H10BrFO2
Molecular Weight	261.09 g/mol
Synonyms	2-Bromo-2-(2-fluorophenyl)acetic acid ethyl ester; Ethyl α-bromo-2-fluorophenylacetate; α-Bromo-2-fluorophenylacetic acid ethyl ester; Ethyl (2-fluorophenyl)(bromo)acetate; 2-Fluorophenylbromoacetic acid ethyl ester; Ethyl 2-fluorophenyl(bromo)acetate; Bromo(2-fluorophenyl)acetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Bromo-2-(2-Fluorophenyl)Acetate is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for advanced intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture ingress and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.