Description

3-Chloro-N-(3-Fluorophenyl)Propanamide is a high-purity fluorinated aromatic amide building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the chloro and fluoro substituents offer valuable sites for further functionalization. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated motifs into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and material science.
• Organic Synthesis Research: A valuable reagent for constructing complex heterocycles and for studying structure-activity relationships (SAR) in academic and industrial R&D.
• Fluorine Chemistry Studies: Employed as a model compound in research focused on the unique properties and reactivity of fluorinated aromatic systems.

Basic Information

Product Name	3-Chloro-N-(3-Fluorophenyl)Propanamide
CAS No.	100638-26-4
Molecular Formula	C9H9ClFNO
Molecular Weight	201.63 g/mol
Synonyms	3-Chloro-N-(3-fluorophenyl)propanamide; N-(3-Fluorophenyl)-3-chloropropanamide; 3-Chloropropanilide, 3'-fluoro-; 3-Chloro-N-(m-fluorophenyl)propanamide; Propanamide, 3-chloro-N-(3-fluorophenyl)-; 100638-26-4; 3-Chloro-N-(3-fluorophenyl)propionamide
EINECS	Contact for details

Quality Control

Our 3-Chloro-N-(3-Fluorophenyl)Propanamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for each batch to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.