Description

1-(m-Chlorophenyl)-4,4,4-Trifluoro-3-Trifluoromethyl-2-Buten-1-Ol is a high-value fluorinated organic intermediate characterized by its unique structure containing both chlorophenyl and trifluoromethyl groups. This compound is critical for synthesizing advanced molecules where the introduction of fluorine atoms is required to modulate biological activity, chemical stability, and lipophilicity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where fluorine substitution enhances efficacy and environmental profile.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals that require specific fluorinated aromatic components.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions and as a ligand precursor in organometallic chemistry.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and novel fluorination methodologies.

Basic Information

Product Name	1-(m-Chlorophenyl)-4,4,4-Trifluoro-3-Trifluoromethyl-2-Buten-1-Ol
CAS No.	100482-51-7
Molecular Formula	C11H7ClF6O
Molecular Weight	304.62 g/mol
Synonyms	3-Chloro-α-(trifluoromethyl)benzyl Alcohol, Trifluoro Derivative; 1-(3-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)but-2-en-1-ol; m-Chlorophenyl Trifluoromethyl Butenol; 3-Chloro-α-(trifluoromethyl)-β,β,β-trifluoroallyl Alcohol; (E/Z)-1-(3-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)but-2-en-1-ol
EINECS	Contact for details

Quality Control

Our production of 1-(m-Chlorophenyl)-4,4,4-Trifluoro-3-Trifluoromethyl-2-Buten-1-Ol adheres to stringent in-process controls and final batch analysis to ensure consistent purity and chemical identity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, isomeric purity, and impurity profiles. We support compliance with cGMP and ISO 9001 standards for traceability and quality management, catering to the rigorous demands of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Isomeric Purity (GC/HPLC)	≥ 95.0% (E/Z ratio as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.