Description

5,5'-[(1,3-Dioxo-1,3-Propanediyl)Bis(Methylimino)]Bis[N,N'-Bis(2,3-Dihydroxypropyl)-2,4,6-Triiodo-1,3-Benzenedicarboxamide] is a high-purity, non-ionic iodinated contrast agent intermediate. This compound matters for its critical role in the synthesis of advanced X-ray and computed tomography (CT) contrast media, providing excellent water solubility and biocompatibility. Pharmaceutical manufacturers and advanced chemical synthesis facilities require this precise intermediate to develop next-generation diagnostic imaging agents.

Application

• Pharmaceutical Intermediate: Primary building block for synthesizing non-ionic, dimeric X-ray contrast media such as Iodixanol and related compounds.
• Diagnostic Imaging Agent Synthesis: Used in the production of contrast agents for angiography, urography, and myelography.
• CT Scan Contrast Media: Key precursor for agents that enhance vascular and tissue imaging in computed tomography.
• Research & Development: Serves as a reference standard and starting material in medicinal chemistry research for novel radiocontrast molecules.
• Custom Synthesis: Employed in the contract manufacturing of specialized, high-osmolality contrast media derivatives.

Basic Information

Product Name	5,5'-[(1,3-Dioxo-1,3-Propanediyl)Bis(Methylimino)]Bis[N,N'-Bis(2,3-Dihydroxypropyl)-2,4,6-Triiodo-1,3-Benzenedicarboxamide]
CAS No.	100311-02-2
Molecular Formula	C37H44I6N6O14
Molecular Weight	1550.18 g/mol
Synonyms	Iodixanol Intermediate; 1,3-Bis(acetamido)-N,N'-bis[2,3-bis(2,3-dihydroxypropylcarbamoyl)-4,6-diiodophenyl]-2-methylaminocarbonylpropane; 5,5'-[2-Hydroxy-1,3-propanediylbis(methylimino)carbonyl]bis[N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide]; Iodixanol API Intermediate; Visipaque™ Intermediate; CT Contrast Agent Intermediate; Non-ionic Dimer Intermediate
EINECS	Contact for details

Quality Control

Our 5,5'-[(1,3-Dioxo-1,3-Propanediyl)Bis(Methylimino)]Bis[N,N'-Bis(2,3-Dihydroxypropyl)-2,4,6-Triiodo-1,3-Benzenedicarboxamide] is manufactured under strict quality systems. We offer material suitable for advanced pharmaceutical synthesis, with quality control adhering to ICH guidelines and current Good Manufacturing Practice (GMP) standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each batch to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and opened under conditions of low humidity to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.