Description

Lhrh, Phe(2)-n-ε-(2,4)-Dinitrophenol-Lys(6)- CAS NO 100304-55-0 is a synthetic peptide derivative, specifically a modified analog of Luteinizing Hormone-Releasing Hormone (LHRH). This compound is a critical research-grade biochemical tool, valued for its role in studying hormone-receptor interactions and signal transduction pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on endocrinology, oncology, and the development of novel therapeutic agents.

Application

• Biochemical Research: A key reagent for investigating the structure-activity relationships (SAR) of LHRH and its receptor binding mechanisms.
• Pharmaceutical Development: Serves as a reference standard or intermediate in the synthesis and screening of potential peptide-based therapeutics targeting hormonal disorders.
• Endocrinology Studies: Used in in vitro and ex vivo assays to study pituitary hormone release and related physiological processes.
• Oncology Research: Applied in research exploring hormone-dependent cancers, such as prostate and breast cancer, where LHRH pathways are implicated.
• Analytical Standard: Employed as a high-purity calibrant in chromatographic (HPLC, LC-MS) and spectroscopic analyses for method development and validation.
• Peptide Chemistry: Acts as a model compound for studying peptide modification, stability, and conjugation techniques in synthetic chemistry labs.

Basic Information

Item	Details
Product Name	Lhrh, Phe(2)-n-ε-(2,4)-Dinitrophenol-Lys(6)- CAS NO 100304-55-0
CAS No.	100304-55-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	LHRH (2-Phe, 6-[N-ε-(2,4-dinitrophenyl)-Lys]); DNP-Lys(6)-LHRH; Luteinizing Hormone-Releasing Hormone analog; GnRH analog (modified); [Phe², Lys(Dnp)⁶]-LHRH; Gonadotropin-Releasing Hormone derivative; Dinitrophenyl-LHRH conjugate; Research Peptide 100304-55-0
EINECS	Contact for details

Quality Control

Our Lhrh, Phe(2)-n-ε-(2,4)-Dinitrophenol-Lys(6)- is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry (MS) for identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical parameters such as assay purity, related substances, and residual solvents to ensure compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. Due to its hygroscopic nature, the product should be stored under desiccant or in a controlled humidity environment. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term stability, store under inert atmosphere (argon or nitrogen) when possible.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.