Description

6-[[2-[(2-Methylpropan-2-Yl)Oxy]-2-Oxoethyl]Amino]Hexanoic Acid is a specialized organic compound with a unique molecular structure combining an aminohexanoic acid backbone with a tert-butyl ester-protected carboxylic acid group. This compound matters as a versatile chemical building block and protected intermediate, enabling precise synthesis in advanced chemical manufacturing. It is primarily needed by research institutions and industrial producers in the pharmaceutical and fine chemical sectors for developing novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a key protected synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a specific amino acid-like spacer.
• Peptidomimetic Research: Used in medicinal chemistry for constructing peptide analogs and mimetics, where its structure can influence bioavailability and metabolic stability.
• Linker Chemistry: Functions as a bifunctional linker molecule in bioconjugation and the development of antibody-drug conjugates (ADCs) or other targeted therapeutics.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for introducing hydrolyzable ester and amide linkages into specialty polymers.
• Organic Synthesis Building Block: Provides a tert-butyl-protected carboxylic acid group, which is stable under many reaction conditions but can be selectively deprotected, offering strategic advantages in complex synthetic routes.
• Biochemical Tool Development: Utilized in the design and synthesis of enzyme inhibitors, probes, and other biochemical tools for life science research.

Basic Information

Product Name	6-[[2-[(2-Methylpropan-2-Yl)Oxy]-2-Oxoethyl]Amino]Hexanoic Acid
CAS No.	100222-98-8
Molecular Formula	C13H25NO4
Molecular Weight	259.34 g/mol
Synonyms	6-[(2-[(tert-Butoxy)-2-oxoethyl]amino)hexanoic acid; 6-[(2-(tert-Butoxy)-2-oxoethyl)amino]caproic acid; N-(tert-Butoxycarbonylmethyl)-6-aminohexanoic acid; Boc-Ahx-OH (common abbreviation); 6-Amino-N-(2-((tert-butoxy)carbonyl)ethyl)hexanamide (alternative IUPAC); tert-Butyl 2-((6-carboxyhexyl)amino)acetate; 100222-98-8; tert-Butyl (6-carboxyhexyl)glycinate
EINECS	Contact for details

Quality Control

Our production of 6-[[2-[(2-Methylpropan-2-Yl)Oxy]-2-Oxoethyl]Amino]Hexanoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets precise customer specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with cGMP and ISO 9001 standards for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.