Description

10,11-Dihydroxydihydroquinidine n-Oxide is a specialized quinidine derivative, a key chiral intermediate and reference standard in advanced organic synthesis. This compound matters for its precise stereochemistry and functional groups, which are critical for developing and calibrating high-value pharmaceutical actives and fine chemicals. It is primarily needed by research institutions, pharmaceutical development labs, and manufacturers of chiral catalysts and analytical standards.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of complex alkaloid-based drug candidates and active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used for method development, calibration, and quality control in HPLC, LC-MS, and other chromatographic analyses within pharmaceutical and research laboratories.
• Asymmetric Catalysis Research: Employed as a ligand precursor or a model compound in the development of new chiral catalysts for stereoselective synthesis.
• Biochemical Research: Utilized in studies investigating ion channel modulation, antiarrhythmic agents, and other biological activities related to cinchona alkaloid derivatives.
• Fine Chemical Synthesis: Acts as a starting material or intermediate for the preparation of other specialized quinidine and quinine analogs with tailored properties.

Basic Information

Product Name	10,11-Dihydroxydihydroquinidine n-Oxide
CAS No.	100182-37-4
Molecular Formula	C₂₀H₂₆N₂O₄
Molecular Weight	358.43 g/mol
Synonyms	10,11-Dihydroxy-10,11-dihydroquinidine N-oxide; Dihydroquinidine 10,11-diol N-oxide; (8S,9R)-10,11-Dihydroxy-6'-methoxycinchonan-9-ol 1-oxide; Quinidine derivative N-oxide; 10,11-Dihydroxydihydroquinidine 1-oxide; Dihydroquinidine N-oxide diol
EINECS	Contact for details

Quality Control

Our 10,11-Dihydroxydihydroquinidine n-Oxide is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0% (KF)
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.