Description

Hemoglobin F-Beech Island is a highly purified, specialized form of fetal hemoglobin (HbF) derived from a specific source. This product is critical for research and development in hematology and diagnostic applications, offering a consistent and well-characterized reference material. It is primarily utilized by biotechnology firms, clinical research organizations, and diagnostic kit manufacturers focused on hemoglobinopathies, prenatal screening, and advanced biomedical studies.

Application

• Diagnostic Reference Standard: Serves as a primary calibrator or control in clinical assays for quantifying fetal hemoglobin (HbF) levels, essential for diagnosing conditions like β-thalassemia and sickle cell disease.
• Biomedical Research: Used as a key reagent in studies investigating the structure, function, and oxygen-binding properties of fetal hemoglobin for potential therapeutic applications.
• Assay Development: Employed in the development and validation of new HPLC, electrophoresis, or immunoassay-based diagnostic kits for hemoglobin variant analysis.
• Quality Control Material: Acts as a high-purity standard for quality assurance programs in clinical laboratories to ensure accuracy and precision of HbF testing.
• Pharmaceutical Research: Investigated in preclinical studies for therapies aimed at reactivating fetal hemoglobin production in patients with hemoglobin disorders.

Basic Information

Product Name	Hemoglobin F-Beech Island
CAS No.	100178-92-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	HbF Beech Island; Fetal Hemoglobin Beech Island; Hemoglobin F (Beech Island variant); γ-globin variant; HbF (Beech Island); Fetal Hb; Glycosylated Fetal Hemoglobin; Hemoglobin F Mutant
EINECS	Contact for details

Quality Control

Our Hemoglobin F-Beech Island is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including purity assessment by HPLC and identity confirmation, to ensure it meets the high standards required for research and diagnostic use. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation. For long-term storage, consider aliquoting and freezing at -20°C or below under inert conditions.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (HPLC/Electrophoresis)	Conforms to standard for HbF Beech Island
Purity (by HPLC)	≥ 95%
Protein Content (Biuret)	Contact for details
Moisture Content (Karl Fischer)	≤ 5.0%
Solubility	Clear solution in specified buffer
Biological Activity (Oxygen Binding)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.