Description

(E)-n-(2-Hydroxy-1,1-Dimethyl-Ethyl)-3-(3-Nitrophenyl)Acrylamide is a specialized acrylamide derivative featuring a nitroaromatic substituent, which is a key structural motif in advanced organic synthesis. This compound matters as a versatile chemical intermediate and pharmacophore building block, enabling the development of novel molecules with targeted biological or material properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways where the nitro and acrylamide groups are crucial.
• Agrochemical Research: Used in developing new herbicides, fungicides, or plant growth regulators, leveraging its reactive structure for creating bioactive molecules.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex organic molecules, including polymers and dyes, via its polymerizable acrylamide group.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers with specific optical or electronic properties.
• Bioconjugation Chemistry: Potential use in creating probes or conjugates for biochemical and diagnostic applications due to its reactive double bond.

Basic Information

Product Name	(E)-n-(2-Hydroxy-1,1-Dimethyl-Ethyl)-3-(3-Nitrophenyl)Acrylamide
CAS No.	100098-62-2
Molecular Formula	C₁₄H₁₈N₂O₄
Molecular Weight	278.31 g/mol
Synonyms	N-(2-Hydroxy-1,1-dimethylethyl)-3-(3-nitrophenyl)-2-propenamide; (E)-N-(2-Hydroxy-1,1-dimethylethyl)-3-(3-nitrophenyl)acrylamide; 2-Propenamide, N-(2-hydroxy-1,1-dimethylethyl)-3-(3-nitrophenyl)-, (E)-; 3-(3-Nitrophenyl)-N-(2-hydroxy-1,1-dimethylethyl)acrylamide; Acrylamide derivative CAS 100098-62-2; N-(tert-Butylglycinol)-3-(3-nitrophenyl)acrylamide
EINECS	Contact for details

Quality Control

Our (E)-n-(2-Hydroxy-1,1-Dimethyl-Ethyl)-3-(3-Nitrophenyl)Acrylamide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.