Description

Ac-D-Ala-OMe is a protected D-alanine derivative, specifically the acetylated methyl ester. This compound is a crucial chiral building block in organic synthesis and peptide chemistry, valued for its role in introducing the D-configuration of alanine into complex molecular structures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptides, peptidomimetics, and active pharmaceutical ingredients (APIs).

Application

• Peptide Synthesis: A key intermediate for the solid-phase and solution-phase synthesis of peptides containing D-alanine residues.
• Pharmaceutical Research: Used in the R&D of therapeutic peptides, antimicrobial peptides, and hormone analogs where D-amino acids enhance metabolic stability.
• Biochemical Studies: Employed as a substrate or inhibitor in enzymatic studies to investigate protease specificity and function.
• Chemical Biology: Serves as a building block for creating labeled probes, molecular tools, and bioactive compound libraries.
• Material Science: Potential use in the synthesis of specialized polymers and biomaterials with tailored properties.

Basic Information

Product Name	Ac-D-Ala-OMe
CAS No.	19914-36-4
Molecular Formula	C6H11NO3
Molecular Weight	145.16 g/mol
Synonyms	N-Acetyl-D-alanine methyl ester; Methyl N-acetyl-D-alaninate; D-Alanine, N-acetyl-, methyl ester; Ac-D-Ala-OMe; (R)-Methyl 2-acetamidopropanoate; N-Acetyl-D-alanine methyl ester; N-Acetyl-D-alanine methyl ester; Methyl (R)-2-acetamidopropanoate
EINECS	Contact for details

Quality Control

Our Ac-D-Ala-OMe is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.