Description

Ioxotrizoic Acid is a specialized iodinated organic compound primarily utilized as a key intermediate in the synthesis of X-ray contrast media. Its molecular structure, featuring a triiodinated benzene ring, is fundamental for creating agents with high radiopacity essential for diagnostic imaging. This high-purity intermediate is critical for pharmaceutical manufacturers and advanced chemical synthesis facilities developing next-generation contrast agents for computed tomography (CT) and angiography.

Application

• Pharmaceutical Intermediate: Primary use as a crucial building block in the synthesis of non-ionic, iodinated X-ray contrast agents.
• Diagnostic Imaging Agent Synthesis: Key precursor for compounds like iopamidol, iohexol, and ioversol used in CT scans.
• Angiography Contrast Media: Serves in the production of contrast agents for vascular and cardiac imaging procedures.
• Research & Development: Used in academic and industrial R&D for developing novel radiopaque materials and studying structure-activity relationships.
• Specialty Chemical Manufacturing: Employed in fine chemical synthesis where a triiodinated aromatic scaffold is required.

Basic Information

Product Name	Ioxotrizoic Acid
CAS No.	19863-06-0
Molecular Formula	C11H9I3N2O4
Molecular Weight	669.92 g/mol
Synonyms	5-Acetamido-2,4,6-triiodo-N-methylisophthalamic Acid; Ioxotrizoate; NSC 113939; 3,5-Bis(acetylamino)-2,4,6-triiodobenzoic Acid; 2,4,6-Triiodo-3,5-diacetamidobenzoic Acid; Acide Ioxotrizoique; Ácido Ioxotrizoico
EINECS	243-357-6

Quality Control

Our Ioxotrizoic Acid is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical intermediate applications. Specifications typically align with in-process control (IPC) parameters for contrast media synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.