Description

8-Hexadecyne is a high-purity, long-chain terminal alkyne with the CAS number 19781-86-3. This compound serves as a versatile and valuable building block in advanced organic synthesis and materials science research. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries. Its terminal alkyne functionality makes it a key intermediate for click chemistry, cross-coupling reactions, and the development of novel molecular architectures.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via Huisgen cycloaddition and Sonogashira coupling reactions.
• Agrochemical Synthesis: Serves as a key precursor for creating novel fungicides, herbicides, and plant growth regulators with tailored properties.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers, dendrimers, and surface-functionalized materials.
• Liquid Crystal & OLED Research: Employed in the development of organic semiconductors and liquid crystal compounds for display technologies.
• Chemical Biology Probes: Utilized for bioconjugation and labeling of biomolecules (proteins, nucleic acids) for diagnostic and research applications.
• Catalyst & Ligand Development: Functions as a substrate for testing and developing new catalytic systems in organic transformations.
• Lubricant & Fuel Additive Research: Investigated as a potential precursor for high-performance synthetic lubricants and fuel additives.

Basic Information

Product Name	8-Hexadecyne
CAS No.	19781-86-3
Molecular Formula	C₁₆H₃₀
Molecular Weight	222.41 g/mol
Synonyms	1-Hexadecyne; Hexadec-1-yne; n-Tetradecylacetylene; Cetylacetylene; 1-Tetradecyne (common misnomer); Terminal Hexadecyne; n-Hexadec-1-yne
EINECS	243-312-9

Quality Control

Our 8-Hexadecyne is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, GC-MS, and NMR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates and ISO 9001 standards for industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. For long-term storage (>12 months), consider storage under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.1%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.