Description

5-Dodecyne is a terminal alkyne compound with a linear twelve-carbon chain, offering a versatile and reactive building block for advanced organic synthesis. Its terminal alkyne functionality makes it a valuable intermediate for constructing more complex molecules through reactions like Sonogashira coupling, click chemistry, and metal-catalyzed transformations. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients, polymers, and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of new drug candidates, particularly for creating acetylene-linked molecular architectures.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators requiring specific alkyne functionalities.
• Material Science & Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers, dendrimers, and conductive materials.
• Organic Synthesis & Research: A fundamental reagent for Sonogashira, Glaser, and other metal-catalyzed coupling reactions in academic and industrial R&D laboratories.
• Liquid Crystal & OLED Materials: Employed in the synthesis of organic semiconductors and liquid crystal compounds for electronic displays.
• Surface Modification & Click Chemistry: Utilized for functionalizing surfaces, nanoparticles, and biomolecules via robust Huisgen cycloaddition (click) reactions.

Basic Information

Product Name	5-Dodecyne
CAS No.	19780-12-2
Molecular Formula	C₁₂H₂₂
Molecular Weight	166.30 g/mol
Synonyms	Dodec-5-yne; 5-Dodecyne; 1-Heptyl-1-pentyne; n-Heptylacetylene; 1-Pentyl-1-heptyne
EINECS	243-306-5

Quality Control

Our 5-Dodecyne is produced under stringent quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including Gas Chromatography (GC) and spectroscopic methods, to verify identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. For long-term storage, we recommend keeping the product under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent degradation. The recommended storage temperature is between 2°C and 25°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	0.76 - 0.78 g/mL
Refractive Index (n20D)	1.430 - 1.435

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.