Description

10-(Tetrahydro-2H-Pyran-2-Yloxy)-1-Decyne is a versatile alkyne derivative featuring a tetrahydropyranyl (THP) protecting group, which is crucial for synthetic organic chemistry. This compound is a valuable building block and intermediate for the controlled synthesis of complex molecules, particularly in pharmaceutical and fine chemical research. It is primarily used by R&D chemists and process development scientists in the life sciences, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides.
• Material Science: Serves as a monomer or precursor for functional polymers and advanced organic materials.
• Academic & Industrial Research: A critical reagent for methodology development and complex natural product synthesis in organic chemistry laboratories.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances.
• Cross-Coupling Reactions: Utilized as a substrate in Sonogashira and other palladium-catalyzed coupling reactions to construct carbon-carbon bonds.

Basic Information

Product Name	10-(Tetrahydro-2H-Pyran-2-Yloxy)-1-Decyne
CAS No.	19754-58-6
Molecular Formula	C15H26O2
Molecular Weight	238.37 g/mol
Synonyms	1-Decyne, 10-(tetrahydro-2H-pyran-2-yloxy)-; 10-(THP-Oxy)-1-decyne; 10-(Tetrahydropyran-2-yloxy)decyne; 2-[(1-Octyn-1-yl)oxy]tetrahydropyran; THP-protected 10-hydroxy-1-decyne; 10-(Oxan-2-yloxy)dec-1-yne; 10-(2-Tetrahydropyranyloxy)-1-decyne
EINECS	Contact for details

Quality Control

Our 10-(Tetrahydro-2H-Pyran-2-Yloxy)-1-Decyne is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.