Description

Ac-Ala-Nhme is a protected alanine derivative, specifically N-Acetyl-L-alanine methylamide, with the CAS registry number 19701-83-8. This compound serves as a crucial building block and intermediate in organic synthesis, particularly for the construction of complex peptides and modified amino acid structures. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers engaged in drug discovery and development of bioactive molecules.

Application

• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to introduce alanine residues.
• Pharmaceutical Intermediates: Serves as a key building block in the research and development of novel active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in studies of enzyme substrates, inhibitors, and metabolic pathways involving modified amino acids.
• Combinatorial Chemistry: A valuable reagent for generating diverse chemical libraries for high-throughput screening in drug discovery.
• Proteomics & Bioconjugation: Can be utilized for the synthesis of peptide probes, tags, and standards used in mass spectrometry and labeling studies.
• Material Science: Potential intermediate for synthesizing specialized polymers and biomaterials with peptide-based backbones.

Basic Information

Product Name	Ac-Ala-Nhme
CAS No.	19701-83-8
Molecular Formula	C6H12N2O2
Molecular Weight	144.17 g/mol
Synonyms	N-Acetyl-L-alanine methylamide; N-Acetyl-L-alanine N'-methylamide; Nα-Acetyl-L-alaninamide, N-methyl-; Ac-L-Ala-NHMe; Ac-Ala-NHCH3; L-Alanine, N-acetyl-, N-methylamide; (S)-2-Acetamido-N-methylpropanamide; Methylamide of N-acetyl-L-alanine
EINECS	Contact for details

Quality Control

Our Ac-Ala-Nhme is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric integrity, and spectroscopic identification (NMR, IR). Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and batch-to-batch consistency for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.