Description

Ganglioside Gm2 Sodium Salt is a high-purity, chemically defined glycosphingolipid, a critical component of cell membranes and a key antigen in biomedical research. Its primary value lies in its role as a specific biomarker and research tool for studying lysosomal storage disorders, particularly Tay-Sachs disease. This compound is essential for researchers and developers in the pharmaceutical, diagnostic, and life science sectors who require reliable, well-characterized biochemicals for assay development, antibody production, and metabolic pathway studies.

Application

• Biomedical Research: Used as a standard antigen in immunological assays to study anti-GM2 antibodies and related autoimmune responses.
• Diagnostic Development: Serves as a critical component in the development of enzyme activity assays and diagnostic kits for Tay-Sachs disease and Sandhoff disease.
• Neuroscience Studies: Employed in research on ganglioside metabolism, neuronal cell signaling, and membrane biophysics.
• Pharmaceutical R&D: Acts as a reference standard and target molecule in drug discovery programs focused on lysosomal storage disorders.
• Vaccine Research: Investigated as a potential target antigen for cancer immunotherapy and vaccine development.
• Biochemical Reagent: Used as a substrate for enzymatic studies involving hexosaminidase A and B enzymes.

Basic Information

Product Name	Ganglioside Gm2 Sodium Salt
CAS No.	19600-01-2
Molecular Formula	C73H130N4NaO31
Molecular Weight	~1570.8 g/mol
Synonyms	GM2 Ganglioside Sodium Salt; II3-α-N-Acetylneuraminosylgangliotetraosylceramide Sodium Salt; Tay-Sachs Ganglioside Sodium Salt; GM2 Sodium Salt; Monosialotetrahexosylganglioside GM2; Asialo-GM2 Sodium Salt (derivative); N-Acetyl-GM2 Sodium Salt; Ganglioside GM2 (Na Salt)
EINECS	Contact for details

Quality Control

Every batch of Ganglioside Gm2 Sodium Salt is produced and analyzed under strict quality protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing comprehensive analytical results from techniques including HPLC, MS, and NMR to confirm high chemical and isomeric purity suitable for sensitive research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, containers should be sealed under an inert atmosphere (e.g., argon or nitrogen) and kept in a desiccated environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95% (Area Percent)
Purity (TLC)	Single major spot
Water Content (KF)	≤ 5.0 %
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details
Biological Activity	Suitable for immunoassay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.